MARK16 is a five-year SNSF PRIMA project (2018-2023) that develops a new research model in digitized biblical sciences, based on a test case found in the New Testament: the last chapter of the Gospel according to Mark. A virtual research environment has been built with a manuscript room as main part (https://mark16.sib.swiss; ISSN 2673-9836). This DaSCH website presents the dataset of the 58 manuscripts of the project. Website of the manuscript room: https://mr-mark16.sib.swiss. The complete list of datasets of the project are available on the CNRS Huma-Num public open repository, Nakala: https://mark16-snsf-prima-project.nakala.fr